Perbedaan Nilai Glukosa Pada Tabung Serum Clot dan Tabung Clot Gel Setelah Ditunda Selama 6 Jam

Ayu Lestari; Denny Juraijin; Aristoteles; Nurhidayanti

doi:10.52523/jhast.v4i2.109

Authors

Ayu Lestari Universitas Muhammadiyah Ahmad Dahlan Palembang
Denny Juraijin IKesT Muhammadyah Palembang
Aristoteles Universitas Muhammadiyah Ahmad Dahlan Palembang
Nurhidayanti Universitas Muhammadiyah Ahmad Dahlan Palembang

DOI:

https://doi.org/10.52523/jhast.v4i2.109

Keywords:

Glucose, Diabetes Mellitus, Clot Activator Tube, Serum Separator Tube

Abstract

Background: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. Delays in blood sample processing can induce glycolysis, leading to decreased serum glucose concentration; thus, the choice of blood collection tube is critical. Objective: To determine the difference in serum glucose levels between Clot Activator Tubes and Serum Separator Tubes (SST) after a 6-hour storage delay. Methods: This quasi-experimental study was conducted at RS Bunda Palembang from June 12 to 19, 2025. A total of 42 specimens were selected using purposive sampling. Glucose levels were evaluated immediately and compared with those measured after a 6-hour delay across both tube types. Results: The mean glucose level tested immediately was 202.04 mg/dL. Following a 6-hour delay, the mean glucose level dropped to 182.50 mg/dL in Clot Activator Tubes and 190.16 mg/dL in SSTs. Statistical analysis revealed a significant difference in glucose stability between the two tube types (p < 0.001). Conclusion: There is a significant difference in serum glucose levels between Clot Activator Tubes and Serum Separator Tubes after a 6-hour delay, with SSTs demonstrating superior performance in minimizing glucose degradation.

References

Ferdianto, Makalah Diabetes Mellitus. Jakarta: Universitas Islam Negeri, 2019.

E. E. Mustofa, J. Purwono, and Ludiana, “Penerapan Senam Kaki Terhasap Kadar Glukosa Darah Pada Pasien Diabetes Melitus Di WIlayah Kerja Puskesmas Purwosari Kec. Metro Utara,” J. Cendikia Muda, vol. 2, no. 1, pp. 78–86, 2022.

Haws, Asuhan Neonatus Rujukan Cepat. Jakarta: EGC, 2021.

Hasdianah, Ilmu Kedokteran Pencegahan dan Komunitas. Jakarta: EGC, 2023.

Dinkes Kota Palembang, Profil Kesehatan Kota Palembang Tahun 2021. 2022.

P. Sagita, E. Apriliana, S. Mussabiq, and T. Soleha, “Pengaruh Pemberian Daun Sirsak Terhadap Penyakit Diabetes,” J. Med. Hutama, vol. 3, no. 1, pp. 1266–1272, 2020.

Sudoyo, Buku Ajar Ilmu Penyakit Dalam. Jakarta: Internal Publishing, 2020.

Y. T. Putri and A. Nusadewiarti, “Penatalaksanaan Pasien Diabetes Melitus Tipe 2 dengan Neuropati dan Retinopati Penatalaksanaan Pasien Diabetes Melitus Tipe 2 dengan Neuropati dan Retinopati Diabetikum Melalui Pendekatan Kedokteran Keluarga,” Medula, vol. 9, no. 4, pp. 631–638, 2020.

Ripani, Intisari Prinsip-Prinsip Ilmu Bedah. Jakarta: EGC, 2019.

A. Furqon, H. Nurmukhlis, and S. Kasiman, “Stabilitas Konsentrasi Glukosa Darah Simpan Jangka Pendek Dalam Tabung Berteknologi Pemisah Jel,” Pharmaciana, vol. 5, no. 2, 2023, doi: 10.12928/pharmaciana.v5i2.2310.

H. A. Gunawan, “Perbandingan Kadar Glukosa Darah Menggunakan Sampel Serum, Plasma Heparin Dan Plasma Naf,” J. Wiyata Penelit. Sains dan Kesehat., vol. 11, no. 1, p. 36, 2024, doi: 10.56710/wiyata.v11i1.785.

Prihandono, “Evaluasi Penggunaan Serum Dan Plasma Yang Disimpan Pada Tabung Cloting Activator Dan Naf Selama 6 Dan 24 Jam Parameter Glukosa Darah Evaluation of Serum and Plasma Usage That Stored on Activator Cloting Tubes and Naf for 6 and 24 Hours of Blood Glucose Pa,” Progr. Stud. D3 Teknol. Lab. Medis, vol. Vol 6, No, 2024.

F. N. Azizah, “Pengaruh Variasi Waktu Penundaan Pemisahan Serum Terhadap Hasil Pemeriksaan Glukosa,” J. Muhammadiyah Med. Lab. Technol., vol. 6, no. 2, pp. 184–191, 2023, doi: 10.30651/jmlt.v6i2.14594.

M. R. Amanatullah, “Kadar Asam Urat Menggunakan Tabung Vacutainer Plain Dan Tabung Vacutainer Serum Separator Dengan Chemistry Analyzer Uric Acid Levels Using Tubes Plain Vacutainer Serum And Vacutainer Tube Separator With Chemistry Analyzer Pendahuluan Laboratorium klinik m,” vol. 24, no. 1, pp. 76–85, 2025.